West of Scotland League Central District Second Division
The Scottish Junior Football Central District Second Division was fourth-tier division of the West Region of the Scottish Junior Football Association.
The three highest-placed teams at the end of the season were promoted to the Central District First Division.
In 2018, the lower leagues in the West Region were reorganised, no longer being split geographically, with the result that the Central First and Second Divisions and the Ayrshire Division merged and were separated into two tiers.
Member clubs for the 2016–17 season
| Club | Location | Home Ground | Finishing position 2015–16 |
| Ashfield | Possilpark, Glasgow | Saracen Park | 11th |
| Carluke Rovers | Carluke | John Cumming Stadium | Central District First Division, 12th |
| Dunipace Juniors | Denny | Westfield Park | Central District First Division, 14th |
| East Kilbride Thistle | East Kilbride | The Showpark | 7th |
| Gartcairn Juniors | Airdrie | MTC Park | 5th |
| Glasgow Perthshire | Possilpark, Glasgow | Keppoch Park | 8th |
| Lanark United | Lanark | Moor Park | 6th |
| Newmains United | Newmains | Victoria Park | 9th |
| Port Glasgow | Port Glasgow | Parklea Community Stadium | 4th |
| Royal Albert | Stonehouse | Tilework Park | 12th |
| St. Anthony's | Cardonald, Glasgow | McKenna Park | Central District First Division, 13th |
| Vale of Leven | Alexandria | Millburn Park | 10th |