Bay K8644


Bay K8644 is a chemical compound that functions as a calcium channel agonist. Bay K8644 is used primarily as a biochemical research tool for this effect. It is a structural analog of nifedipine with positive inotropic activity, and as an aromatic it is highly lipid soluble.

Mechanism of action

Bay K8644 targets voltage-sensitive dihydropyridine calcium channels. It is the first positive inotropic agent shown to act specifically and directly on calcium channels.