Clovis Oncology


Clovis Oncology is a small pharmaceutical company which mainly markets products for treatment in oncology. Clovis was founded in 2009 and is headquartered in Boulder, Colorado. The company is a publicly traded company on NASDAQ under the symbol "CLVS" and is in the NASDAQ Biotechnology Index with several products in its product pipeline. As of December 31, 2017 the company was not profitable and had incurred losses in each year since its inception in April 2009.

Pipeline

Its products include:
The company was developing rociletinib, as a treatment for non-small cell lung cancer. A phase III trial was completed in April 2016 and had it been approved it would have competed with AstraZeneca's Tagrisso. According to the company web site as of November 2016 studies on the drug are no longer accepting new patients, but Clovis would continue to supply the drug to patients whose physicians had recommended continued treatment.
In September 2018, the company and two former executives agreed to a $20M settlement with the Securities and Exchange Commission on claims it exaggerated to investors the efficacy of Roci in patient trials.

Rucaparib

is a PARP inhibitor in Phase II and III clinical trials for advanced ovarian cancer.

Lucitanib

is a VEGFR inhibitor. it is also an inhibitor of FGFR1 and FGFR2 and has undergone clinical trials for advanced solid tumors.