Dequalinium


Dequalinium is a quaternary ammonium cation and bolaamphiphile commonly available as the dichloride salt. The bromide, iodide, acetate, and undecenoate salts are known as well. Dequalinium chloride is the active ingredient of several medications:
Dequadin an antiseptic and disinfectant. It is a topical bacteriostat. It is used in wound dressings and mouth infections and may also have antifungal action. It may cause skin ulceration.
Fluomizin, vaginal tablets containing 10 mg dequalinium chloride, are used for treating vaginal bacterial conditions.
The dequalinium dication is symmetrical, containing two quaternary quinolinium units linked by an N-decylene chain.

Applications

Dequalinium salts may be used to treat malaria. As dequalinium chloride, it can be used in lozenges to cure tonsillitis, but this is not effective in cases of streptococci infections.