From the formulae of the previous section it appears that the time component of the four-force is the power expended,, apart from relativistic corrections. This is only true in purely mechanical situations, when heat exchanges vanish or can be neglected. If the full thermo-mechanical case, not only work, but also heat contributes to the change in energy, which is the time component of the energy–momentum covector. The time component of the four-force includes in this case a heating rate, besides the power. Note that work and heat cannot be meaningfully separated, though, as they both carry inertia. This fact extends also to contact forces, that is, to the stress-energy-momentum tensor. Therefore, in thermo-mechanical situations the time component of the four-force is not proportional to the power but has a more generic expression, to be given case by case, which represents the supply of internal energy from the combination of work and heat, and which in the Newtonian limit becomes.
In general relativity the relation between four-force, and four-acceleration remains the same, but the elements of the four-force are related to the elements of the four-momentum through a covariant derivative with respect to proper time. In addition, we can formulate force using the concept of coordinate transformations between different coordinate systems. Assume that we know the correct expression for force in a coordinate system at which the particle is momentarily at rest. Then we can perform a transformation to another system to get the corresponding expression of force. In special relativity the transformation will be a Lorentz transformation between coordinate systems moving with a relative constant velocity whereas in general relativity it will be a general coordinate transformation. Consider the four-force acting on a particle of mass which is momentarily at rest in a coordinate system. The relativistic force in another coordinate system moving with constant velocity, relative to the other one, is obtained using a Lorentz transformation: where. In general relativity, the expression for force becomes with covariant derivative. The equation of motion becomes where is the Christoffel symbol. If there is no external force, this becomes the equation for geodesics in the curved space-time. The second term in the above equation, plays the role of a gravitational force. If is the correct expression for force in a freely falling frame, we can use then the equivalence principle to write the four-force in an arbitrary coordinate :