Reyes signed with the San Diego Padres as an international free agent in 2011. He made his professional debut in 2012 with the Dominican Summer League Padres and spent the whole season there, batting.267/.360/.416 with four home runs and 37 RBIs in 67 games. He played 2013 with the Arizona League Padres and Eugene Emeralds where he compiled a.292 batting average with four home runs and 34 RBIs in 57 games, 2014 with the Fort Wayne TinCaps where he posted a.248 batting average with 11 home runs and 59 RBIs in 128 games, and 2015 back with Fort Wayne where he slashed.255/.320/.393 with eight home runs and 62 RBIs in 123 games. Reyes played 2016 with the Lake Elsinore Storm where he batted.278 with 16 home runs and 83 RBIs in 130 games, and 2017 with the San Antonio Missions where he compiled a.258 batting average with 25 home runs, 102 RBIs, and a.785 OPS in 135 games. He started 2018 with the El Paso Chihuahuas. After batting.346/.442/.738 with 14 home runs and 38 RBIs in 36 games for El Paso, he was promoted to the San Diego Padres on May 14. Reyes made his Major League debut on May 14, 2018, against the Colorado Rockies, getting the start in right field after outfielders Wil Myers and Hunter Renfroe had both been placed on the disabled list. Reyes hit his first MLB home run onMay 21 at Nationals Park Reyes was optioned back to Triple-A El Paso on May 31 when Myers returned to the Padres. He returned to the team on July 10 and made regular starts in right field until he was optioned again on July 21 when Myers returned from a different injury. Reyes was recalled for a span of 10 games in July, but only saw 12 at-bats, serving mostly as a pinch hitter. He returned to the team in early August when Myers again went to the disabled list. After this fourth promotion, Reyes improved his approach at the plate and raised his average from.221 to.280 through the end of the season while making regular starts in right field. On August 30, he hit a walk-off home run in the 13th inning against Colorado. Reyes finished the season with an.838 OPS and 16 home runs in 261 at-bats and 71 starts in right field. Reyes had surgery in the off-season to repair a torn right knee meniscus.
Cleveland Indians
On July 31, 2019, the Padres traded Reyes to the Cleveland Indians in a three-team trade that also included the Cincinnati Reds. The Indians also acquired Logan Allen and minor leaguer Victor Nova from the Padres and Yasiel Puig and minor league pitcher Scott Moss from the Reds, while the Reds acquired Trevor Bauer from the Indians and the Padres acquired minor leaguer Taylor Trammell from the Reds. In 2019 in aggregate he batted.237/.304/.468. He made contact with the lowest percentage of pitches he swung at of all major league batters.
