Pearson started his career as a chemist's assistant, but changed his interests after attending a lecture on plants by A. C. Seward at Eastbourne in 1892. He taught for a while and was awarded a scholarship to Christ's College, Cambridge in 1896, obtaining a first class in the Natural Science Tripos. Pearson published two papers in 1898, dealing with Bowenia spectabilis, a member of the Stangeriaceae from Australia. In the same year he explored the patanas in Ceylon for six months, having been awarded a Worts Travelling Scholars Fund. For this ecological dissertation he received the Walsingham Medal from Cambridge, the marine biologistErnest William MacBride having been the first recipient in 1893. At Cambridge he was appointed Assistant Curator of the herbarium under Harry Marshall Ward. Here taxonomy engaged his interest and he received a Frank Smart Studentship. The following year found him at the Royal Botanic Gardens at Kew where he was Assistant for India. His interest in Verbenaceae led to his description of the family for Harvey & Sonder'sFlora Capensis. In 1903 Pearson became the first Harry Bolus Professor of Botany at the South African College. In 1904 he set off for South West Africa on the first of several expeditions with the object of studying the monotypicWelwitschia. This expedition was cut short by the first of the so-called Herero Wars. In 1907 he made a second attempt in the company of E. E. Galpin who had previously accompanied him on cycad-hunting trips to the Eastern Cape. His papers on the ecology, morphology and embryology of Welwitschia, led to a CantabrigianDSc in 1907, which in turn led to a study of the closely related Gnetum, to which end he went on a collecting expedition to Angola in 1909. During this time he wrote an account of the Thymelaeaceae for the Flora of Tropical Africa. Living in Cape Town and keenly aware of the floristic wealth of the Cape Peninsula, Pearson had become an ardent campaigner for the establishing of a botanical garden. He made an impassioned appeal to the authorities and the public at his 1910 presidential address to the South African Association for the Advancement of Science. As a consequence the Botanical Society of South Africa was formed in 1912 and a deputation was despatched to make representations to the Prime Minister, Louis Botha. The campaign found a powerful supporter in Sir Lionel Phillips, who introduced the necessary bill in the House of Assembly in 1913. An area which Cecil Rhodes had bequeathed to the public, was set aside and Kirstenbosch National Botanical Garden came into being. Pearson was appointed as the first director, with J. W. Matthews as curator. On Pearson's death he was buried in Kirstenbosch, his epitaph reading "If ye seek his monument, look around". He is commemorated in the genus Pearsonia and several specific epithets. The 1914 volume 140 of Curtis's Botanical Magazine is dedicated to his memory. The Harold Pearson Chair of Botany at the University of Cape Town was founded in his honour, and the HW Pearson Building is named after him. This botanist is denoted by the author abbreviationH.Pearson when citing a botanical name.