List of American Airlines destinations
flies to 95 domestic destinations and 95 international destinations in 55 countries. The list includes the city, country, and the airport's name, with the airline's hubs, seasonal destinations, and previously served destinations marked where applicable. This list does not include airports served by only American Eagle, the airline's regional brand.
| Country | City | Airport | Notes | Refs |
| Antigua and Barbuda | Saint John's | V. C. Bird International Airport | ||
| Argentina | Buenos Aires | Ministro Pistarini International Airport | ||
| Argentina | Córdoba | Ingeniero Aeronáutico Ambrosio L.V. Taravella International Airport | ||
| Aruba | Oranjestad | Queen Beatrix International Airport | ||
| Australia | Sydney | Sydney Airport | ||
| Bahamas | Nassau | Lynden Pindling International Airport | ||
| Bahamas | Freeport | Freeport International Airport | ||
| Barbados | Bridgetown | Grantley Adams International Airport | ||
| Belgium | Brussels | Brussels Airport | ||
| Belize | Belize City | Philip S. W. Goldson International Airport | ||
| Bermuda | St. George's Parish | L.F. Wade International Airport | ||
| Bolivia | La Paz | El Alto International Airport | ||
| Bolivia | Santa Cruz de la Sierra | Viru Viru International Airport | ||
| Bonaire | Kralendijk | Flamingo International Airport | ||
| Brazil | Belo Horizonte | Tancredo Neves International Airport | ||
| Brazil | Brasília | Brasília International Airport | ||
| Brazil | Curitiba | Afonso Pena International Airport | ||
| Brazil | Manaus | Eduardo Gomes International Airport | ||
| Brazil | Porto Alegre | Salgado Filho International Airport | ||
| Brazil | Recife | Recife/Guararapes–Gilberto Freyre International Airport | ||
| Brazil | Rio de Janeiro | Rio de Janeiro–Galeão International Airport | ||
| Brazil | Salvador da Bahia | Deputado Luís Eduardo Magalhães International Airport | ||
| Brazil | São Paulo | São Paulo–Guarulhos International Airport | ||
| Canada | Calgary | Calgary International Airport | ||
| Canada | Vancouver | Vancouver International Airport | ||
| Canada | Toronto | Toronto Pearson International Airport | ||
| Canada | Montreal | Montréal–Pierre Elliott Trudeau International Airport | ||
| Cayman Islands | George Town | Owen Roberts International Airport | ||
| Chile | Santiago de Chile | Arturo Merino Benítez International Airport | ||
| China | Beijing | Beijing Capital International Airport | ||
| China | Shanghai | Shanghai Pudong International Airport | ||
| Colombia | Barranquilla | Ernesto Cortissoz International Airport | ||
| Colombia | Bogotá | El Dorado International Airport | ||
| Colombia | Cali | Alfonso Bonilla Aragón International Airport | ||
| Colombia | Cartagena | Rafael Núñez International Airport | ||
| Colombia | Medellín | José María Córdova International Airport | ||
| Colombia | Pereira | Matecaña International Airport | ||
| Costa Rica | Liberia | Daniel Oduber Quirós International Airport | ||
| Costa Rica | San José | Juan Santamaría International Airport | ||
| Croatia | Dubrovnik | Dubrovnik Airport | ||
| Cuba | Camagüey | Ignacio Agramonte International Airport | ||
| Cuba | Havana | José Martí International Airport | ||
| Cuba | Holguín | Frank País Airport | ||
| Cuba | Santa Clara | Abel Santamaría Airport | ||
| Cuba | Santiago de Cuba | Antonio Maceo Airport | ||
| Cuba | Varadero | Juan Gualberto Gómez Airport | ||
| Curaçao | Willemstad | Curaçao International Airport | ||
| Czech Republic | Prague | Václav Havel Airport Prague | ||
| Dominican Republic | La Romana | La Romana International Airport | ||
| Dominican Republic | Puerto Plata | Gregorio Luperón International Airport | ||
| Dominican Republic | Punta Cana | Punta Cana International Airport | ||
| Dominican Republic | Santiago de los Caballeros | Cibao International Airport | ||
| Dominican Republic | Santo Domingo | Las Américas International Airport | ||
| Ecuador | Guayaquil | José Joaquín de Olmedo International Airport | ||
| Ecuador | Quito | Mariscal Sucre International Airport | ||
| El Salvador | San Salvador | El Salvador International Airport | ||
| Finland | Helsinki | Helsinki Airport | ||
| France | Paris | Charles de Gaulle Airport | ||
| Germany | Berlin | Berlin Tegel Airport | ||
| Germany | Düsseldorf | Düsseldorf Airport | ||
| Germany | Frankfurt | Frankfurt Airport | ||
| Germany | Munich | Munich Airport | ||
| Guadeloupe | Pointe-à-Pitre | Pointe-à-Pitre International Airport | ||
| Greece | Athens | Athens International Airport | ||
| Grenada | St. George's | Maurice Bishop International Airport | ||
| Guatemala | Guatemala City | La Aurora International Airport | ||
| Guyana | Georgetown | Cheddi Jagan International Airport | ||
| Haiti | Cap-Haïtien | Hugo Chávez International Airport | ||
| Haiti | Port-au-Prince | Toussaint Louverture International Airport | ||
| Honduras | Roatán | Juan Manuel Gálvez International Airport | ||
| Honduras | San Pedro Sula | La Mesa International Airport | ||
| Honduras | Tegucigalpa | Toncontín International Airport | ||
| Hong Kong, China | Hong Kong | Hong Kong International Airport | ||
| Hungary | Budapest | Budapest Ferenc Liszt International Airport | ||
| Iceland | Reykjavík | Keflavík International Airport | ||
| India | Bengaluru | Kempegowda International Airport | ||
| India | Delhi | Indira Gandhi International Airport | ||
| Ireland | Dublin | Dublin Airport | ||
| Ireland | Shannon | Shannon Airport | ||
| Israel | Tel Aviv | Ben Gurion International Airport | ||
| Italy | Bologna | Bologna Guglielmo Marconi Airport | ||
| Italy | Milan | Milan Malpensa Airport | ||
| Italy | Rome | Leonardo da Vinci–Fiumicino Airport | ||
| Italy | Venice | Venice Marco Polo Airport | ||
| Jamaica | Kingston | Norman Manley International Airport | ||
| Jamaica | Montego Bay | Sangster International Airport | ||
| Japan | Nagoya | Chubu Centrair International Airport | ||
| Japan | Osaka | Kansai International Airport | ||
| Japan | Tokyo | Haneda Airport | ||
| Japan | Tokyo | Narita International Airport | ||
| Martinique | Fort-de-France | Martinique Aimé Césaire International Airport | ||
| Mexico | San José del Cabo | Los Cabos International Airport | ||
| Mexico | Mexico City | Mexico City International Airport | ||
| Mexico | Zihuatanejo | Ixtapa-Zihuatanejo International Airport | ||
| Mexico | Guadalajara | Miguel Hidalgo y Costilla Guadalajara International Airport | ||
| Mexico | Puerto Vallarta | Licenciado Gustavo Díaz Ordaz International Airport | ||
| Mexico | Oaxaca | Oaxaca International Airport | ||
| Mexico | Puebla | Puebla International Airport | ||
| Mexico | Cancún | Cancún International Airport | ||
| Mexico | Cozumel | Cozumel International Airport | ||
| Netherlands | Amsterdam | Amsterdam Airport Schiphol | ||
| New Zealand | Auckland | Auckland Airport | ||
| New Zealand | Christchurch | Christchurch Airport | ||
| Nicaragua | Managua | Augusto C. Sandino International Airport | ||
| Panama | Panama City | Tocumen International Airport | ||
| Paraguay | Asunción | Silvio Pettirossi International Airport | ||
| Peru | Lima | Jorge Chávez International Airport | ||
| Portugal | Lisbon | Lisbon Airport | ||
| Russia | Moscow | Domodedovo International Airport | ||
| Saint Kitts and Nevis | Basseterre | Robert L. Bradshaw International Airport | ||
| Saint Lucia | Vieux Fort | Hewanorra International Airport | ||
| Saint Vincent and the Grenadines | Kingstown | Argyle International Airport | ||
| Sint Maarten | Philipsburg | Princess Juliana International Airport | ||
| South Korea | Seoul | Incheon International Airport | ||
| Spain | Barcelona | Barcelona–El Prat Josep Tarradellas Airport | ||
| Spain | Madrid | Adolfo Suárez Madrid–Barajas Airport | ||
| Switzerland | Zürich | Zurich Airport | ||
| Trinidad and Tobago | Port of Spain | Piarco International Airport | ||
| Turks and Caicos Islands | Providenciales | Providenciales International Airport | ||
| United Kingdom | Birmingham | Birmingham Airport | ||
| United Kingdom | London | Gatwick Airport | ||
| United Kingdom | London | Heathrow Airport | ||
| United Kingdom | Manchester | Manchester Airport | ||
| United Kingdom | Edinburgh | Edinburgh Airport | ||
| United Kingdom | Glasgow | Glasgow Airport | ||
| United States | Anchorage | Ted Stevens Anchorage International Airport | ||
| United States | Fairbanks | Fairbanks International Airport | ||
| United States | Phoenix | Phoenix Sky Harbor International Airport | ||
| United States | Tucson | Tucson International Airport | ||
| United States | Yuma | Yuma International Airport | ||
| United States | Bentonville | Northwest Arkansas Regional Airport | ||
| United States | Burbank | Hollywood Burbank Airport | ||
| United States | Fresno | Fresno Yosemite International Airport | ||
| United States | Los Angeles | Los Angeles International Airport | ||
| United States | Oakland | Oakland International Airport | ||
| United States | Ontario | Ontario International Airport | ||
| United States | Palm Springs | Palm Springs International Airport | ||
| United States | Sacramento | Sacramento International Airport | ||
| United States | San Diego | San Diego International Airport | ||
| United States | San Francisco | San Francisco International Airport | ||
| United States | San Jose | San Jose International Airport | ||
| United States | Santa Ana | John Wayne Airport | ||
| United States | Santa Barbara | Santa Barbara Municipal Airport | ||
| United States | Colorado Springs | Colorado Springs Airport | ||
| United States | Denver | Denver International Airport | ||
| United States | Hayden | Yampa Valley Airport | ||
| United States | Montrose | Montrose Regional Airport | ||
| United States | Vail | Eagle County Regional Airport | ||
| United States | Hartford | Bradley International Airport | ||
| United States | Washington, D.C. | Washington Dulles International Airport | ||
| United States | Washington, D.C. | Ronald Reagan Washington National Airport | ||
| United States | Fort Lauderdale | Fort Lauderdale–Hollywood International Airport | ||
| United States | Fort Myers | Southwest Florida International Airport | ||
| United States | Jacksonville | Jacksonville International Airport | ||
| United States | Miami | Miami International Airport | ||
| United States | Orlando | Orlando International Airport | ||
| United States | Sarasota | Sarasota Bradenton International Airport | ||
| United States | Pensacola | Pensacola International Airport | ||
| United States | Tampa | Tampa International Airport | ||
| United States | West Palm Beach | Palm Beach International Airport | ||
| United States | Atlanta | Hartsfield–Jackson Atlanta International Airport | ||
| United States | Honolulu | Daniel K. Inouye International Airport | ||
| United States | Kahului | Kahului Airport | ||
| United States | Kailua-Kona | Kona International Airport | ||
| United States | Lihue | Lihue Airport | ||
| United States | Boise | Boise Airport | ||
| United States | Chicago | O'Hare International Airport | ||
| United States | Indianapolis | Indianapolis International Airport | ||
| United States | Des Moines | Des Moines International Airport | ||
| United States | Wichita | Wichita Dwight D. Eisenhower National Airport | ||
| United States | Louisville | Louisville International Airport | Lexington Bluegrass Regional Airport | |
| United States | Baton Rouge | Baton Rouge Metropolitan Airport | ||
| United States | New Orleans | Louis Armstrong New Orleans International Airport | ||
| United States | Portland | Portland International Jetport | ||
| United States | Baltimore | Baltimore–Washington International Airport | ||
| United States | Boston | Logan International Airport | ||
| United States | Worcester | Worcester Regional Airport | ||
| United States | Detroit | Detroit Metropolitan Airport | ||
| United States | Minneapolis | Minneapolis−Saint Paul International Airport | ||
| United States | Kansas City | Kansas City International Airport | ||
| United States | St. Louis | St. Louis Lambert International Airport | ||
| United States | Bozeman | Bozeman Yellowstone International Airport | ||
| United States | Missoula | Missoula International Airport | ||
| United States | Omaha | Eppley Airfield | ||
| United States | Las Vegas | McCarran International Airport | ||
| United States | Reno | Reno–Tahoe International Airport | ||
| United States | Newark | Newark Liberty International Airport | ||
| United States | Albuquerque | Albuquerque International Sunport | ||
| United States | Santa Fe | Santa Fe Municipal Airport | ||
| United States | Albany | Albany International Airport | ||
| United States | Buffalo | Buffalo Niagara International Airport | ||
| United States | New York City | John F. Kennedy International Airport | ||
| United States | New York City | LaGuardia Airport | ||
| United States | Rochester | Greater Rochester International Airport | ||
| United States | Syracuse | Syracuse Hancock International Airport | ||
| United States | Charlotte | Charlotte Douglas International Airport | ||
| United States | Greensboro | Piedmont Triad International Airport | ||
| United States | Raleigh | Raleigh–Durham International Airport | ||
| United States | Wilmington | Wilmington International Airport | ||
| United States | Bismarck | Bismarck Municipal Airport | ||
| United States | Fargo | Hector International Airport | ||
| United States | Akron | Akron–Canton Regional Airport | ||
| United States | Cincinnati | Cincinnati/Northern Kentucky International Airport | ||
| United States | Cleveland | Cleveland Hopkins International Airport | ||
| United States | Columbus | John Glenn Columbus International Airport | ||
| United States | Dayton | Dayton International Airport | ||
| United States | Toledo | Toledo Express Airport | ||
| United States | Oklahoma City | Will Rogers World Airport | ||
| United States | Tulsa | Tulsa International Airport | ||
| United States | Portland | Portland International Airport | ||
| United States | Redmond | Redmond Municipal Airport | ||
| United States | Harrisburg | Harrisburg International Airport | ||
| United States | Philadelphia | Philadelphia International Airport | ||
| United States | Pittsburgh | Pittsburgh International Airport | ||
| United States | San Juan | Luis Muñoz Marín International Airport | ||
| United States | Providence | T. F. Green Airport | ||
| United States | Knoxville | McGhee Tyson Airport | ||
| United States | Memphis | Memphis International Airport | ||
| United States | Nashville | Nashville International Airport | ||
| United States | Austin | Austin–Bergstrom International Airport | ||
| United States | Dallas | Dallas/Fort Worth International Airport | ||
| United States | El Paso | El Paso International Airport | ||
| United States | Houston | George Bush Intercontinental Airport | ||
| United States | Houston | William P. Hobby Airport | ||
| United States | San Antonio | San Antonio International Airport | ||
| United States | Salt Lake City | Salt Lake City International Airport | ||
| United States | Saint Croix | Henry E. Rohlsen Airport | ||
| United States | Saint Thomas | Cyril E. King Airport | ||
| United States | Norfolk | Norfolk International Airport | ||
| United States | Richmond | Richmond International Airport | ||
| United States | Seattle | Seattle–Tacoma International Airport | ||
| United States | Spokane | Spokane International Airport | ||
| United States | Milwaukee | Milwaukee Mitchell International Airport | ||
| United States | Jackson | Jackson Hole Airport | ||
| Uruguay | Montevideo | Carrasco International Airport | ||
| Venezuela | Caracas | Simón Bolívar International Airport | ||
| Venezuela | Maracaibo | La Chinita International Airport | ||
| Venezuela | Valencia | Arturo Michelena International Airport |