List of IARC Group 2A Agents - Probably carcinogenic to humans Group 2A by the International Agency for Research on Cancerexposure circumstances that pose a risk. This designation is applied when there is limited evidence of carcinogenicity in humans as well as sufficient evidence of carcinogenicity in experimental animals . In some cases, an agent may be classified in this group when there is inadequate evidence of carcinogenicity in humans along with sufficient evidence of carcinogenicity in experimental animals and strong evidencelimited evidence of carcinogenicity in humans.Agents Substances Acrylamide Adriamycin Androgenic steroids Azacitidine BCNU Captafol Chloral Chloral hydrate Chloramphenicol α-Chlorinated toluenes and benzoyl chloride CCNU 4-Chloro-o -toluidine Chlorozotocin Cisplatin Cyclopentapyrene|Cyclopentapyrene Diazinon Dibenzacridine|Dibenzacridine Dibenzanthracene|Dibenzanthracene Dibenzopyrene|Dibenzopyrene Dichloromethane 4,4'-Dichlorodiphenyltrichloroethane Diethyl sulfate Dieldrin, and aldrin metabolized to dieldrin Dimethylcarbamoyl chloride Dimethylformamide 1,2-Dimethylhydrazine Dimethyl sulfate Epichlorohydrin Ethylene dibromide Ethyl carbamate N-Ethyl-N-nitrosourea Glycidol Glyphosate Hydrazine Indium phosphide Heterocyclic amine formation in meat#Heterocyclic amines, meat, and cancer|2-Amino-3-methylimidazoquinoline Lead compounds, inorganic Malathion 5-Methoxypsoralen Methyl methanesulfonate Mercaptobenzothiozole MNNG N-Methyl-N-nitrosourea Nitrate or nitrite under conditions that result in endogenous nitrosation Nitrogen mustard 1-Nitropyrene N-Nitrosodiethylamine N-Nitrosodimethylamine Nitrotoluene 6-Nitrochrysene Phenacetin Pioglitazone Polybrominated biphenyls Procarbazine hydrochloride 1,3-Propane sultone Silicon carbide whiskers Styrene Styrene-7,8-oxide Teniposide Tetrabromobisphenol A 3,3',4,4'-Tetrachloroazobenzene Tetrachloroethylene Tetrafluoroethylene 1,2,3-Trichloropropane Tris phosphate Vinyl bromide Vinyl fluoridePathogens Malaria Human papillomavirus type 68 Merkel cell polyomavirusMixtures Bitumens, occupational exposure to oxidized bitumens and their emissions during roofing Creosotes High-temperature frying , emissions from Household combustion of biomass fuel , indoor emissions from Non-arsenical insecticides Red meat Coffee, mate, and very hot beverages Very hot beverages at above 65 °CExposure circumstances Art glass, glass containers and pressed ware Carbon electrode manufacture Cobalt metal with tungsten carbide Hairdresser or barber Petroleum refining Shift work that involves circadian disruption
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