List of state leaders in the 16th century


;State leaders in the 15th century – State leaders in the 17th centuryState leaders by year
This is a list of state leaders in the 16th century AD.
These polities are generally sovereign states, but excludes minor dependent territories, whose leaders can be found listed under territorial governors in the 16th century. For completeness, these lists can include colonies, protectorates, or other dependent territories that have since gained sovereignty.

Africa

Africa: Central

Angola
Cameroon
Chad
Congo: Belgian
Congo: French
São Tomé and Príncipe
Great Lakes area
Horn of Africa area
Madagascar
Ifriqiya
Egypt
Sudan
Morocco
Mozambique
Benin
Burkina Faso
Cape Verde
Guinea-Bissau
Niger
Nigeria
Senegal
in 1821.

Asia: Central

Kazakhstan
Russia
Tajikistan
Tibet
Uzbekistan
Ismail I and Muhammad Shaybani in 1510.|288x288px
China: Ming dynasty
Japan
Korea
Mongolia
Brunei
Cambodia
Indonesia
Laos
Malaysia
Myanmar / Burma
Philippines
Thailand
Vietnam
Bengal
Maldives
Nepal
Sri Lanka
Turkey
Yemen

Europe: British Isles

Scotland
Ireland
Holy Roman Empire in Germany
Bohemia, Hungary
Poland
Prussia
Austrian
Bavarian
Burgundian
Franconian
Electoral Rhenish
Lower Rhenish–Westphalian
Upper Rhenish
Lower Saxon
Upper Saxon
Swabian
Holy Roman Empire in Italy
Southern Italy
Navarre
Portugal
Spain

Americas: North

Incas