Louis Ferdinand was born in Potsdam as the third in succession to the throne of the German Empire, after his father, German Crown Prince William and elder brother Prince Wilhelm of Prussia. The monarchy was abolished after Germany's revolution in 1918. When Louis Ferdinand's older brother Prince Wilhelm renounced his succession rights to marry a member of the untitled nobility in 1933, Louis Ferdinand replaced him as second in the line of succession to the defunct German throne after the Crown Prince. Louis Ferdinand was educated in Berlin and deviated from his family's tradition by not pursuing a military career. Instead, he travelled extensively and settled for some time in Detroit, where he befriended Henry Ford and became acquainted with Franklin Delano Roosevelt, among others. He held a great interest in engineering. Recalled from the United States upon his brother's renunciation of the throne, he got involved in the German aviation industry, but was barred by Hitler from taking any active part in German military activities. Louis Ferdinand dissociated himself from the Nazis after this. He was not involved in the 20 July Plot against Hitler in 1944 but was interrogated by the Gestapo immediately afterwards. He was released shortly afterwards. He married his second cousin once removed, Grand Duchess Kira Kirillovna of Russia, in 1938 in first a Russian Orthodox ceremony in Potsdam and then a Lutheran ceremony in Huis Doorn, Netherlands. Kira was the second daughter of Grand Duke Kyril Vladimirovich and Princess Victoria Melita of Saxe-Coburg and Gotha. The couple had four sons and three daughters. His two eldest sons both renounced their succession rights in order to marry commoners. His third son and heir apparent, Prince Louis Ferdinand died in 1977 during military maneuvers, and thus his one-year-old grandson Georg Friedrich, Prince of Prussia became the new heir apparent to the Prussian and German Imperial throne. Upon Louis Ferdinand's death in 1994, Georg Friedrich became the pretender to the thrones and head of the Hohenzollern family. After the reunification of Germany, Louis Ferdinand arranged to have the remains of several Hohenzollern members reinterred at the imperial vault in Potsdam. The Prince was popular. In 1968 Der Spiegel reported that in a survey of their readers by Quick magazine about who would be the most honorable person to become President of the Federal Republic of Germany, Louis Ferdinand, the only of twelve candidates who was not a politician, won with 39.8% before Carlo Schmid and Ludwig Erhard. In a similar survey by the Bild tabloid, readers chose Louis Ferdinand by 55.6%. In an interview with Quick, the Prince indicated that he might accept the presidency but would not relinquish his claim to the crown of emperor of Germany. Prince Ferdinand of Hohenzollern, a member of the senior Swabian branch of the Hohenzollern dynasty, Hohenzollern-Sigmaringen, is his godson.
Children
Prince Friedrich Wilhelm of Prussia, married firstly Waltraud Freydag on 22 August 1967 in Plön, divorced 1975; secondly Ehrengard von Reden on 23 April 1976; thirdly Sibylle Kretschmer on 23 March 2004. He renounced his succession rights on 18 September 1967. His son Philip is from his first marriage, and his other children from his second.
*Philip Kirill Prinz von Preußen ; married Anna Christine Soltau on 28 June 1994, with issue:
**Paul Wilhelm
**Maria Luise
**Elisabeth Christine
**Anna Sophie
**Johanna Amalie
**Timotheus Friedrich
*Friedrich Wilhelm Prinz von Preußen ; married Baroness Anna von Salza und Lichtenau on 30 April 2009, with issue:
**Friedrich Wilhelm
**Charlotte
*Viktoria-Luise Prinzessin von Preußen married Hereditary Prince Ferdinand of Leiningen on 29 April 2017 civilly and on 16 September 2017 religiously.
*Joachim Albrecht Prinz von Preußen married Countess Angelina of Solms-Laubach on 29 June 2019.
**Georgina
Prince Michael of Prussia ; married firstly Jutta Jörn on 23 September 1966 in Kaiserwerth, Düsseldorf, with issue. He married secondly Brigitte von Dallwitz on 23 June 1982, without issue. He renounced his succession rights on 29 August 1966.
*Michaela Prinzessin von Preußen, married Jürgen Wessolly on 14 February 2000, with issue.
Prince Louis Ferdinand of Prussia ; married Countess Donata of Castell-Rüdenhausen on 23 May 1975 civilly and 24 May 1975 religiously at Rüdenhausen, who bore him two children
*Georg Friedrich, Prince of Prussia ; married Princess Sophie of Isenburg on 25 August 2011 civilly and 27 August 2011 religiously, they have four children:
**Prince Carl Friedrich Franz Alexander of Prussia