Mary Jane Guthrie


Mary Jane Guthrie was an American zoologist and cytologist known for her studies of cytoplasm in reproductive and endocrine cells.

Early life and education

Guthrie was born in New Bloomfield, Missouri. She graduated from the University of Missouri with a bachelor's degree in 1916 and a master's degree in 1918, then earned her Ph.D. in zoology at Bryn Mawr College in 1922. While working towards her Ph.D., Guthrie served as a zoology instructor and demonstrator.

Career and research

Returning to Missouri after earning her Ph.D., Guthrie spent the majority of her career at her alma mater, becoming an assistant professor in 1922, associate professor in 1927, and full professor in 1937. Guthrie was known for her writing about zoology; she wrote several textbooks on the subject that were widely used. Guthrie left the University of Missouri for Wayne State University in Detroit in 1950, and stayed there until her 1960 retirement; in 1951 she was given a concurrent appointment at the Detroit Institute for Cancer Research. She cultured ovarian tissue in vitro, a significant achievement at the time, and used her cultures to study ovarian cancer.
Despite her success, Guthrie was denied funding because of her gender, including one instance where she was not funded by the Rockefeller Foundation.

Honors and awards

Professional memberships:
Fellowships and awards: