Neurotensin receptor 1


Neurotensin receptor type 1 is a protein that in humans is encoded by the NTSR1 gene. For a crystal structure of NTS1, see pdb code 4GRV.

Function

Neurotensin receptor 1, also called NTR1, belongs to the large superfamily of G-protein coupled receptors and is considered a class-A GPCR. NTSR1 mediates multiple biological through modulation by neurotensin, such as low blood pressure, high blood sugar, low body temperature, antinociception, and regulation of intestinal motility and secretion.

Ligands