Pepe

• People

Politicians

• Porfirio Lobo Sosa, known as Pepe, candidate for the Presidency of Honduras
• José Mujica, known as El Pepe, president of Uruguay
• José Gregorio Liendo, known as "comandante Pepe", "compañero Pepe", or "loco Pepe", Chilean political activist
• José Rizal, Filipino nationalist

  Musicians

• Pepe Romero, Spanish classical and flamenco guitarist
• Pepe Aguilar, American folklore singer
• Pépé Kallé, Congolese Soukous singer
• Pepe Smith, real name Joseph William Feliciano Smith, Filipino rock singer and drummer

  Sportsmen

• Pepe Frias , Puerto Rican MLB player
• Pepe Pearson, American football player
• Pepe Reina, Spanish footballer
• Juan Ignacio Sánchez known as Pepe Sánchez, Argentine basketball player
• Pepe Soares, real name José Manuel Soares, Portuguese footballer
• Marcos Paulo Aguiar de Jesus, known as Pepe, Brazilian footballer
• Pepe, real name José Macia, Brazilian footballer
• Pepe, real name Képler Laveran Lima Ferreira, Brazilian-born Portuguese footballer
• Pepê, real name Eduardo Gabriel Aquino Cossa, Brazilian footballer
• Pepê, real name João Pedro Vilardi Pinto, Brazilian footballer

  Surname

• Cécé Pepe, French footballer
• Florestano Pepe, Italian soldier, brother of Guglielmo
• Gabriele Pepe, Italian soldier, cousin of Guglielmo
• Guglielmo Pepe, Italian general
• Nico Pepe, Italian actor
• Nicolas Pépé, French-Ivorian footballer
• Osman Pepe, Turkish politician
• Simone Pepe, Italian footballer
• Vincenzo Pepe, Italian footballer

  Fictional characters

• Pepe el Toro, main character in the series of films Nosotros los Pobres, Ustedes los Ricos and Pepe el Toro
• Pepé Le Pew, in the Warner Bros. Looney Tunes and Merrie Melodies series of cartoons
• Justin Vincenzo Pepé Russo and Geraldo Pepé Russo, characters from the TV series Wizards of Waverly Place
• Pepe, in the manga series Shugo Chara!
• Pepe, from Unseen Academicals by Terry Pratchett
• Pepe the Frog, Internet meme from the comic series Boy's Club
• Pepe the King Prawn, a Muppet character
• Pepe Waccabrada, from the anime Bleach by Tite Kubo
• Pépé Torres the young killer in John Steinbeck's short story Flight 1938