Primera División de México Invierno 2001
Primera División de México Invierno 2001 is the second part of a two tournament season in Association football in Mexico. It began on July 21, 2001, and ended on November 25, the end of the season. La Piedad was promoted to Primera División de México, making possible that 19 teams took part in the Mexican First Division instead of the 18 teams in previous seasons. Pachuca defeated UANL in the final, their second title win.
Overview
| Team | City | Stadium | - |
| América | Mexico City | Azteca | - |
| Atlante | Mexico City | Azul | - |
| Atlas | Guadalajara, Jalisco | Jalisco | - |
| Celaya | Celaya, Guanajuato | Miguel Alemán Valdés | - |
| Cruz Azul | Mexico City | Azul | - |
| Guadalajara | Guadalajara, Jalisco | Jalisco | - |
| Irapuato | Irapuato, Guanajuato | Sergio León Chávez | - |
| La Piedad | La Piedad, Michoacán | Juan N. López | - |
| León | León, Guanajuato | León | - |
| Morelia | Morelia, Michoacán | Morelos | - |
| Monterrey | Monterrey, Nuevo León | Tecnológico | - |
| Necaxa | Mexico City | Azteca | - |
| Pachuca | Pachuca, Hidalgo | Hidalgo | - |
| Puebla | Puebla, Puebla | Cuauhtémoc | - |
| Santos Laguna | Torreón, Coahuila | Corona | - |
| Toluca | Toluca, State of Mexico | Nemesio Díez | - |
| UAG | Zapopan, Jalisco | Tres de Marzo | - |
| UANL | San Nicolás de los Garza, Nuevo León | Universitario | - |
| UNAM | Mexico City | Olímpico Universitario |
Final standings (groups)
League table
Results
Top goalscorers
Players sorted first by goals scored, then by last name. Only regular season goals listed.| Rank | Player | Club | Goals |
| 1 |  Martín Rodríguez | Irapuato | 12 |
| 2 |  Alex Fernandes | Morelia | 11 |
| 3 |  José Manuel Abundis | Atlante | 10 |
| 4 | Jared Borgetti | Santos Laguna | 9 |
| 4 |  José Luis Calderón | Atlas | 9 |
| 4 | Walter Silvani | Pachuca | 9 |
| 4 |  Iván Zamorano | América | 9 |
| 8 | Claudinho | La Piedad | 8 |
| 8 | Vicente Sánchez | Toluca | - |
| 8 | Miguel Zepeda | Cruz Azul | - |
Source:
Playoffs
Bracket
Quarterfinals
UANL won 4–1 on aggregate.----
Toluca won 3–1 on aggregate.
----
2–2 on aggregate. Pachuca advanced for being the higher seeded team.
----
Cruz Azul won 4–2 on aggregate.
Semifinals
1–1 on aggregate. UANL advanced for being the higher seeded team.----
Pachuca won 5–3 on aggregate.