Relaxin receptor


The relaxin receptors are a subclass of four closely related G protein-coupled receptors that bind relaxin peptide hormones.
Below is list of human relaxin receptors, their endogenous peptide hormones, and what down stream enzymes are activated or inhibited by the receptor.
receptor/geneligandsactivatesinhibits
relaxin 1, relaxin 2, relaxin 3adenylate cyclase, protein kinase A, protein kinase C,
phosphatidylinositol 3-kinase, extracellular signal-regulated kinases
relaxin 1, relaxin 2, insulin-like 3adenylate cyclase
relaxin 3Erk1/2 signalingadenylate cyclase
relaxin 3, insulin-like 3adenylate cyclase