Small nucleolar RNA SNORD75
Small Nucleolar RNA SNORD75 is a non-coding RNA molecule which functions in the biogenesis of other small nuclear RNAs. This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA and also often referred to as a guide RNA.
U75 belongs to the C/D box class of snoRNAs which contain the C and D box motifs. Most of the members of the box C/D family function in directing site-specific 2′-O-methylation of substrate RNAs.
The mouse snoRNA Z19 is orthologous to human U75. U75 is predicted to guide the 2′-O-ribose methylation of 28S ribosomal RNA residue C4032.
In humans U75 shares the same non-protein coding host gene with 9 other snoRNAs.
