List of estrogen esters
This is a list of estrogen esters, or ester prodrugs of estrogens. It includes esters, as well as ethers, of steroidal estrogens like estradiol, estrone, and estriol and of nonsteroidal estrogens like the stilbestrols diethylstilbestrol and hexestrol.
Esters of steroidal estrogens
Estradiol esters
Marketed
Many esters of estradiol have been marketed, including the following major esters:- Estradiol acetate
- Estradiol benzoate
- Estradiol cypionate
- Estradiol dipropionate
- Estradiol enantate
- Estradiol undecylate
- Estradiol valerate
- Polyestradiol phosphate
- Cloxestradiol acetate
- Estradiol benzoate butyrate
- Estradiol butyrylacetate
- Estradiol dibutyrate
- Estradiol dienantate
- Estradiol diundecylate
- Estradiol diundecylenate
- Estradiol furoate
- Estradiol hemisuccinate
- Estradiol hexahydrobenzoate
- Estradiol palmitate
- Estradiol phenylpropionate
- Estradiol pivalate
- Estradiol propionate
- Estradiol propoxyphenylpropionate
- Estradiol stearate
- Estradiol sulfate
- Estramustine phosphate
Never marketed
- Estradiol 3-furoate
- Estradiol 3-propionate
- Estradiol 17β-
- Estradiol acetate benzoate
- Estradiol 17β-acetate
- Estradiol 17β-benzoate
- Estradiol acetylsalicylate
- Estradiol anthranilate
- Estradiol arachidonate
- Estradiol benzoate cyclooctenyl ether
- Estradiol caprylate
- Estradiol cyclooctyl acetate
- Estradiol decanoate
- Estradiol diacetate
- Estradiol dioleate
- Estradiol dipalmitate
- Estradiol distearate
- Estradiol disulfate
- Estradiol glucuronide
- Estradiol sulfate glucuronide
- Estradiol linoleate
- Estradiol oleate
- Estradiol phosphate
- Estradiol salicylate
- Estradiol sulfamate
- Estradiol undecylenate
- Estrapronicate
- Orestrate
- Alestramustine
- Atrimustine
- Estradiol mustard
- Estramustine
- Estromustine
Estrone esters
Marketed
Esters of estrone that have been marketed include:- Estrone acetate
- Estrone sulfate
- * Estropipate
- Estrone tetraacetylglucoside
Never marketed
- Estrone benzoate
- Estrone cyanate
- Estrone enanthate
- Estrone enanthate benzilic acid hydrazone
- Estrone glucuronide
- Estrone phosphate
- Estrone propionate
- Estrone sulfamate
Estriol esters
Marketed
Esters of estriol that have been marketed include:- Estriol 3-glucuronide
- Estriol acetate benzoate
- Estriol glucuronide
- Estriol succinate
- * Estriol sodium succinate
- Estriol sulfate
- Estriol sulfate glucuronide
- Estriol tripropionate
- Polyestriol phosphate
Never marketed
- Estriol dihexanoate
- Estriol dipropionate
- Estriol phosphate
- Estriol sulfamate
- Estriol triacetate
Ethinylestradiol esters
Marketed
The following esters of ethinylestradiol exist and have been marketed:- Ethinylestradiol sulfonate
Never marketed
- Ethinylestradiol benzoate – the 3-benzoate ester of ethinylestradiol
- Ethinylestradiol N,N-diethylsulfamate – the 3-sulfamate ester of ethinylestradiol
- Ethinylestradiol pyrrolidinosulfonate – the 3-pyrrolidinosulfonate ester of ethinylestradiol
- Ethinylestradiol sulfamate – the 3-sulfamate ester of ethinylestradiol
- Ethinylestradiol sulfate
Esters of other steroidal estrogens
Marketed
The following esters of other estrogens exist and have been marketed:- Hydroxyestrone diacetate – the 3,16α-diacetate ester of 16α-hydroxyestrone
Ethers of steroidal estrogens
Marketed
A number of estrogen ethers also exist and have been marketed, including:- Clomestrone – the 3-methyl ether of 16α-chloroestrone
- Cloxestradiol acetate – the O,O-diacetate ester of cloxestradiol
- Mestranol – the 3-methyl ether of ethinylestradiol
- Moxestrol – the 11β-methoxy derivative of ethinylestradiol
- Nilestriol – the 3-cyclopentyl ether of ethinylestriol
- Promestriene – the 3-propyl and 17β-methyl diether of estradiol
- Quinestradol – the 3-cyclopentyl ether of estriol
- Quinestrol – the 3-cyclopentyl ether of ethinylestradiol
Never marketed
- Cloxestradiol – the 17β-chloral hemiacetal ether of estradiol
- Estradiol benzoate cyclooctenyl ether – the 17β-cyclooctenyl ether of estradiol 3-benzoate
- Estradiol 3-saccharinylmethyl ether – the 3- ether of estradiol
- Estradiol 3-tetrahydropyranyl ether – the 3- ether of estradiol
- Estradiol 17β-tetrahydropyranyl ether – the 17β- ether of estradiol
- Estrone methyl ether – the 3-methyl ether of estrone
- Mytatrienediol – the 3-methyl ether of 16α-methyl-16β-epiestriol
- Orestrate – the 17β- ether of estradiol 3-propionate
Esters of nonsteroidal estrogens
Diethylstilbestrol esters
Marketed
Major esters of diethylstilbestrol include:Less commonly used esters of diethylstilbestrol include:
- Diethylstilbestrol diacetate
- Diethylstilbestrol dilaurate
- Diethylstilbestrol dipalmitate
- Diethylstilbestrol disulfate
Never marketed
- Diethylstilbestrol sulfate
- Furostilbestrol
- Polydiethylstilbestrol phosphate
- ICI-85966
Hexestrol esters
Marketed
- Hexestrol diacetate
- Hexestrol dicaprylate
- Hexestrol diphosphate
- Hexestrol dipropionate
- Hexestrol phosphate
Never marketed
- Phenestrol
Esters of other nonsteroidal estrogens
Marketed
- Dienestrol diacetate
- Methestrol dipropionate
Ethers of nonsteroidal estrogens