Outline of immunology

Essence of immunology

• Branch of Biomedical science
• Immune system
• Immunity

  Branches of immunology

• Classical immunology
• Clinical immunology
• Computational immunology
• Diagnostic immunology
• Evolutionary immunology
• Systems immunology
• Immunomics
• Immunoproteomics
• Immunophysics
• Immunochemistry
• Ecoimmunology
• Immunopathology
• Nutritional immunology
• Psychoneuroimmunology
• Reproductive immunology
• Circadian immunology
• Immunotoxicology
• Palaeoimmunology
• Tissue-based immunology

  History of immunology

• Timeline of immunology

  General immunological concepts

• Immunity:
• Tolerance
• Antigen
• Immunogenetics
• Phagocytosis
• Intrinsic immunity
• Leukocyte extravasation
• Cross-presentation
• Immune repertoire
• Original antigenic sin
• Antigen presentation
• Immunological synapse
• Co-stimulation

  Components of the immune system

  Adaptive immune system

  Innate immune system

• SAP
• SAA
• Alpha 1-antichymotrypsin
• Alpha 1-antitrypsin
• Alpha 2-macroglobulin
• C-reactive protein
• Ceruloplasmin
• C3
• Ferritin
• Fibrin
• Haptoglobin
• Hemopexin
• Orosomucoid
• Serum albumin
• Transferrin

  Organs of the immune system

  Primary Lymphoid Organs

  Secondary Lymphoid Organs

Cells of the immune system

  Myeloid Cells

  Lymphoid Cells

  Others

  Hematopoiesis

Molecules of the Immune System

Immune receptors

   Antigen receptors

   Pattern recognition receptors (PRRs)

• TLR1
• TLR2
• TLR3
• TLR4
• TLR5
• TLR6
• TLR7
• TLR8
• TLR9
• TLR10
• TLR11
• TLR12
• TLR13
• MRC1
• MRC2
• DEC205
• DC-SIGN
• Langerin
• CLEC10A
• CLEC5A
• Dectin 1
• MICL
• CLEC2
• DNGR1
• Dectin 2
• BDCA2
• Mincle
• DCIR
• MSR1
• MARCO
• SCARA3
• SCARA4
• SCARA5
• SCARB1
• SCARB2
• CD36
• CD68
• LOX-1
• FPR1
• FPR2
• FPR3
• NOD1
• NOD2
• NLRC3
• NLRC4
• NLRC5
• NLRP1
• NLRP2
• NLRP3
• NLRP4
• NLRP5
• NLRP6
• NLRP7
• NLRP8
• NLRP9
• NLRP10
• NLRP11
• NLRP12
• NLRP13
• NLRP14
• RIG-I
• MDA5
• LGP2
• Mannan-binding lectin
• Surfactant protein A
• Surfactant protein D
• CL-L1
• CL-P1
• CL-K1
• PGLYRP1
• PGLYRP2
• PGLYRP3
• PGLYRP4
• FCN1
• FCN2
• FCN3

     Complement receptors

   Fc receptors

   Cytokine receptors

   Natural killer cell receptors

• NCR1
• NCR2
• NCR3
• NKG2A
• NKG2B
• NKG2C
• NKG2D
• NKG2E
• NKG2H
• KIR2DL1
• KIR2DL2
• KIR2DL3
• KIR2DL4
• KIR2DL5A
• KIR2DL5B
• KIR2DS1
• KIR2DS2
• KIR2DS3
• KIR2DS4
• KIR2DS5
• KIR3DL1
• KIR3DL2
• KIR3DL3

     Others

• LILRA1
• LILRA2
• LILRA3
• LILRA4
• LILRA5
• LILRA6
• LILRB1
• LILRB2
• LILRB3
• LILRB4
• LILRB5

  Antibodies

• Immunoglobulin A
• * IgA1
• * IgA2
• Immunoglobulin D
• Immunoglobulin E
• Immunoglobulin G
• * IgG1
• * IgG2
• * IgG3
• * IgG4
• Immunoglobulin M

  Cytokines

• Chemokines
• Interferons
• * Interferon type I
• ** IFN-α
• ** IFN-β
• ** IFN-ω
• * Interferon type II
• ** IFN-γ
• Interleukins
• Tumor necrosis factors
• Colony stimulating factors

  MHCs

• MHC class I
• HLA-A
• HLA-B
• HLA-C
• HLA-E
• HLA-F
• HLA-G
• MHC class II
• HLA-DM
• * α
• * β
• HLA-DO
• * α
• * β
• HLA-DP
• * α1
• * β1
• HLA-DQ
• * α1
• * α2
• * β1
• * β2
• * β3
• HLA-DR
• * α
• * β1
• * β3
• * β4
• * β5

  Complement proteins

• Early stage
• Middle stage
• Late stage
• Complement pathway inhibitors

  Antimicrobial peptides

Transcription factors

• NF-κB
• AP-1
• Interferon regulatory factors
• NFAT
• T-bet - T_H1 differentiation
• GATA3 - T_H2 differentiation
• RORγT - T_H17 differentiation
• BCL6 - T_FH differentiation
• FoxP3 - T_reg differentiation

  Signaling pathways

• JAK-STAT signaling pathway
• TGF beta signaling pathway
• TLR signalling pathway

  Cell adhesion molecules (CAMs)

• Integrins - Obligate heterodimers of one alpha and one beta subunits
• Immunoglobulin superfamily CAMs
• Cadherins
• Selectins
• Others

  Others

• CD69
• Sphingosine-1-phosphate receptors
• Co-stimulatory molecules

  Immune system disorders

Hypersensitivity and Allergy

Immunodeficiency

Cancers of the immune system

Myeloid diseases

Inflammatory diseases

Immunoproliferative immunoglobulin disorders

Lymphatic organ disease

Immunologic techniques and tests

• Flow cytometry
• Mass cytometry
• Histology
• Adoptive cell transfer
• Experiments in immunology
• Genetically modified mouse
• Immunofluorescence
• Immunofixation
• Immunoadsorption
• MHC multimer
• Hybridoma technology

  Immunology and Health

• Prevention
• Immunostimulants
• Immunotherapy
• Artificial induction of immunity
• Immunization
• Vaccination
• Organ transplantation

  Immunologists

Immunology lists

• List of autoimmune diseases
• List of immunologists
• List of viruses
• List of human clusters of differentiation
• List of vaccine ingredients
• List of allergens
• List of cytokines
• List of cytokine receptors
• List of pattern recognition receptors
• List of tissue-resident macrophages
• List of branches of immunology
• List of acute-phase proteins